New advances in fatty acids as antimalarial, antimycobacterial and antifungal agents
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چکیده
منابع مشابه
Cryptolepine and development of new antimalarial agents
Natural product-derived drugs exemplified by quinine, isolated from South American Cinchona species and artemisinin discovered in China are of immense importance for the treatment of malaria. Although malaria parasites resistant to artemisinin have not yet been found in malaria patients, the need for new antimalarial agents remains. The burden of malaria is heaviest in Africa where over a milli...
متن کاملCryptolepine and development of new antimalarial agents
Natural product-derived drugs exemplified by quinine, isolated from South American Cinchona species and artemisinin discovered in China are of immense importance for the treatment of malaria. Although malaria parasites resistant to artemisinin have not yet been found in malaria patients, the need for new antimalarial agents remains. The burden of malaria is heaviest in Africa where over a milli...
متن کاملMixtures of Quaternary Ammonium Compounds and Long-chain Fatty Acids as Antifungal Agents
KULL, F. C. (CIBA Pharmaceutical Products Inc., Summit, N. J.), P. C. EISMAN, H. D. SYLWESTROWICZ, AND R. L. MAYER. Mixtures of quaternary ammonium compounds and long-chain fatty acids as antifungal agents. Appl. Microbiol. 9:538-541. 1961.-The influence of undecylenic acid on the fungistatic effect of phenoxyethyldimethyldodecylammonium bromide (Domiphen bromide) against Trichophyton mentagrop...
متن کاملMixturs of quaternary ammonium compounds and long-chain fatty acids as antifungal agents.
The influence of undecylenic acid on the fungistatic effect of phenoxyethyldimethyldodecylammonium bromide (Domiphen bromide) against Trichophyton mentagrophytes was investigated. The unsaturated fatty acid was found to enhance the fungistatic activity of Domiphen bromide against this organism. The ratio of concentrations of these agents has a marked influence on the results of in vitro tests f...
متن کاملSynthesis of new 1,3-thiazoline-2-thiones as potential antimycobacterial agents
As a continuation of our efforts in developing new antimycobacterial agents, a series of new 1,3-thiazolidine-2-thione derivatives were synthesized. The chemical structures of the compounds were elucidated by FT-IR, 1H-NMR and Mass spectra. The analysis of theoretical toxicity risks,drug-likeness and drug-score for these series using Osiris program showed acceptable results.
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ژورنال
عنوان ژورنال: Progress in Lipid Research
سال: 2008
ISSN: 0163-7827
DOI: 10.1016/j.plipres.2007.10.002